Source: | Rabbit | Gene Id: | 5511 |
Isotype: | IgG | Swiss Prot: | Q12972 |
purity: | Affinity purification |
Background: |
This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008] |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 40 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | activator of RNA decay, ARD-1, ARD1, EC 3.1.4.-, NIPP1, nuclear inhibitor of protein phosphatase-1, PP1R8, PPP1R8, PPR8, protein phosphatase 1, regulatory inhibitor subunit 8 |
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