Source: | Rabbit | Gene Id: | 10602 |
Isotype: | IgG | Swiss Prot: | Q9UKI2 |
purity: | Affinity purification |
Background: |
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. This protein can interact with CDC42, as well as with the ras homolog gene family, member Q (ARHQ/TC10). Expression of this protein in fibroblasts has been shown to induce pseudopodia formation. [provided by RefSeq |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 28 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Binder of Rho GTPases 2, BORG2, CDC42 effector protein (Rho GTPase binding) 3, Cdc42 effector protein 3, CDC42EP3, CEP3, CRIB-containing BORG2 protein, FLJ46903, MSE55-related Cdc42-binding protein, MSE55-related protein, UB1 |
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