| No | Size | Price | Availability | |
| ARP10435-61 | 50ul | 1500.00 | In Stock |  |
| ARP10435-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 10435 |
| Isotype: | IgG | Swiss Prot: | O14613 |
| purity: | Affinity purification |
| Background: |
| CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 28 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Cdc42 effector protein 2, Binder of Rho GTPases 1 |
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