Source: | Rabbit | Gene Id: | 285489 |
Isotype: | IgG | Swiss Prot: | Q18PE1 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq |
Reactivity | Human, Mouse |
Tested applications | WB IHC IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 60 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Dok-7, downstream of tyrosine kinase 7 |
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