Source: | Rabbit | Gene Id: | 5207/5210 |
Isotype: | IgG | Swiss Prot: | P16118/Q16877 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012] |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 54 kDa |
Recommended Dilutions |
WB 1:500-1:1000
|
Immunogen | A synthetic peptide |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1, 6PF-2-K/Fru-2, 6-P2ASE liver isozyme, 6-phosphofructo-2-kinase, Fructose-2, 6-bisphosphatase, PFKFB1, F6PK, PFRX |
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