TOP3B Rabbit Polyclonal Antibody
No Size Price Availability  
ARP8940-61 50ul 1500.00 In Stock
ARP8940-61 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 8940
Isotype: IgG Swiss Prot: O95985
purity: Affinity purification
Background:
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described. [provided by RefSeq
Reactivity Human, Mouse
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 96 kDa
Recommended Dilutions
WB 1:500-1:1000
Immunogen A synthetic peptide
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym DNA topoisomerase 3-beta-1, EC 5.99.1.2, DNA topoisomerase III beta-1, TOP3B, TOP3B1
This product is for research use only, not for diagnostic or therapeutic use!

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