| No | Size | Price | Availability | |
| ARP9448-62 | 50ul | 1500.00 | In Stock |  |
| ARP9448-62 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 9448 |
| Isotype: | IgG | Swiss Prot: | O95819 |
| purity: | Affinity purification |
| Background: |
| HGK (MAP4K4 or mitogen-activated protein kinase kinase kinase kinase 4) is a serine/threonine kinase that belongs to the mammalian STE20/MAP4K kinase family involved in response to environmental stress and cytokines such as TNF-α (1-3). HGK specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway and increases AP-1-mediated transcriptional activity in vivo (1). HGK is broadly expressed in many types of human cancer and cancer cell lines and plays an important role in cell transformation, invasiveness, adhesion and migration (4,5). |
| Reactivity | Human, Mouse |
| Tested applications | WB IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 142 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | EC 2.7.11.1, HPK/GCK-like kinase HGK, M4K4, MAP4K4, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck interacting kinase, hepatocyte progenitor kinase-like/germinal center kinase-like kinase, mitogen-activated protein kinase kinase kinas |
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