
| Source: | Rabbit | Gene Id: | 472 |
| Isotype: | IgG | Swiss Prot: | Q13315 |
| purity: | Affinity purification |
| Background: |
| ATM encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1 |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 350 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:200
|
| Immunogen | Peptide sequence around aa.1979~1983 (E-G-S-Q-S) derived from Human ATM. |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Ataxia telangiectasia mutated homolog, Ataxia telangiectasia mutated, kinase ATM |
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