| No | Size | Price | Availability | |
| ARPF076-61 | 50ul | 1500.00 | In Stock |  |
| ARPF076-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7020/7021 |
| Isotype: | IgG | Swiss Prot: | P05549/Q92481 |
| purity: | Affinity purification |
| Background: |
| AP-2 alpha Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 49 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human AP-2 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Activating enhancer-binding protein 2-alpha, Activator protein 2, AP-2, AP-2 transcription factor, AP-2alpha, AP2-alpha, AP2A, AP2TF, BOFS, FLJ51761, TFAP2, TFAP2A, transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha), Transcript |
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