Source: | Rabbit | Gene Id: | 3172 |
Isotype: | IgG | Swiss Prot: | P41235/Q14541 |
purity: | Affinity purification |
Background: |
HNF4 alpha a nuclear transcription factor which binds DNA as a homodimer. Controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic gene, alpha 1-antitrypsin, apolipoprotein CIII, and transthyretin genes. May be essential for development of the liver, kidney and intestine. Mutations have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 52 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human HNF4alpha /gamma |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | FLJ39654, hepatic nuclear factor 4 alpha, hepatocyte nuclear factor 4, alpha, Hepatocyte nuclear factor 4-alpha, HNF-4-alpha, HNF4, HNF4A, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, HNF4alpha10/11/12, MODY, MODY1, NR2A1, NR2A21, Nuclear receptor subfamily 2 group |
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