Source: | Rabbit | Gene Id: | 26277 |
Isotype: | IgG | Swiss Prot: | Q9BSI4 |
purity: | Affinity purification |
Background: |
TINF2 Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Monomer. |
Reactivity | Human |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 53 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A synthetic peptide derived from human TINF2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | (TRF1)-interacting nuclear factor 2 variant 1, TERF1 (TRF1)-interacting nuclear factor 2, TERF1-interacting nuclear factor 2, TIN2, TINF2, TRF1-interacting nuclear protein 2 |
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