Source: | Rabbit | Gene Id: | 25816 |
Isotype: | IgG | Swiss Prot: | O95379 |
purity: | Affinity purification |
Background: |
TNFAIP8 Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. Belongs to the TNFAIP8 family. Induced by nuclear factor-KB (NF-KB) and TNF. Induction by TNF depends upon activation of NF-KB. |
Reactivity | Human, Mouse |
Tested applications | WB IHC IF ICC |
Clonality | Polyclonal Antibody |
Calculated MW | 23 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:100-1:500
ICC 1:100-1:500
|
Immunogen | A synthetic peptide derived from human TFIP8 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | GG2-1, Head and neck tumor and metastasis-related protein, MDC-3.13, NDED, NF-kappa-B-inducible DED-containing protein, SCC-S2, SCCS2, TFIP8, TNF alpha-induced protein 8, TNF-induced protein GG2-1, TNFAIP8, Tumor necrosis factor alpha-induced protein 8, t |
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