| No | Size | Price | Availability | |
| ARP7133-61 | 50ul | 1500.00 | In Stock |  |
| ARP7133-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7133 |
| Isotype: | IgG | Swiss Prot: | P20333 |
| purity: | Affinity chromatography |
| Background: |
| TNF-R2 Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IF ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 48 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
IF 1:100-1:500
ICC 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human TNF-R2 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CD120b, p75, p75 TNF receptor, p75TNFR, p80 TNF-alpha receptor, soluble TNFR1B variant 1, TBP-2, TBPII, TNF-R-II, TNF-R2, TNF-R75, TNF-RII, TNFBR, TNFR-II, TNFR1B, TNFR2, TNFR80, TNFRSF1B, TNR1B, tumor necrosis factor beta receptor, tumor necrosis factor |
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