Source: | Rabbit | Gene Id: | 7030 |
Isotype: | IgG | Swiss Prot: | P19532 |
purity: | Affinity chromatography |
Background: |
TFE3 Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 62 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human TFE3 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | class E basic helix-loop-helix protein 33, DKFZp761J1810, Putative uncharacterized protein DKFZp761J1810, RCCP2, TFE3, TFEA, transcription factor binding to IGHM enhancer 3 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.