| No | Size | Price | Availability | |
| ARP53615-61 | 50ul | 1500.00 | In Stock |  |
| ARP53615-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 53615 |
| Isotype: | IgG | Swiss Prot: | O95983 |
| purity: | Affinity chromatography |
| Background: |
| MBD3 methyl-CpG binding (MBD) proteins appear to bind differentially methylated domains (DMDs) of DNA, to recruit repression complexes, and to silence the locus. The methyl CpG binding domain of human MBD3 may not directly bind mCpG but does interact with the NuRD/Mi2 components HDAC1 and MTA2. Plays a role in histone deacetylation and nucleosome remodeling. Increased levels have been reported in lung cancer and glioblastomas and may be a therapeutic target. |
| Reactivity | Human, Mouse |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 33 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
|
| Immunogen | A synthetic peptide derived from human MBD3 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | MBD3, methyl-CpG binding domain protein 3, Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3 |
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