| No | Size | Price | Availability | |
| ARP2263-61 | 50ul | 1500.00 | In Stock |  |
| ARP2263-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2263 |
| Isotype: | IgG | Swiss Prot: | P21802 |
| purity: | Affinity chromatography |
| Background: |
| FGFR2 a receptor tyrosine kinase of the highly-conserved FGFR family that binds fibroblast growth factor (FGF). Mutations are associated with many craniosynostotic syndromes and bone malformations. Mutations cause syndromes with defects in facial and limb development, including Crouzon syndrome, Beare-Stevenson cutis gyrata syndrome, Pfeiffer syndrome, Apert syndrome, and Jackson-Weiss syndrome. Somatic mutations seen in gastric cancer. Amplified in gastric, breast and some B cell cancers, but deleted in glioblastoma Twenty splice-variant isoforms have been described. Note: This description may include information from UniProtKB. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 92 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human FGFR2 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | bacteria-expressed kinase, BEK, BEK fibroblast growth factor receptor, BFR-1, CD332, CEK3, CFD1, ECT1, FGF receptor, FGFR-2, FGFR2, Fibroblast growth factor receptor 2, FLJ98662, hydroxyaryl-protein kinase, JWS, K-sam, Keratinocyte growth factor receptor |
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