| No | Size | Price | Availability | |
| ARP1876-61 | 50ul | 1500.00 | In Stock |  |
| ARP1876-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1876 |
| Isotype: | IgG | Swiss Prot: | O75461 |
| purity: | Affinity chromatography |
| Background: |
| E2F6 Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F-6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 31 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human E2F6 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | E2F transcription factor 6, E2F transcription factor 6, isoform 1, E2F-6, E2F6, MGC111545, Transcription factor E2F6 |
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