Source: | Rabbit | Gene Id: | 1874/1875 |
Isotype: | IgG | Swiss Prot: | Q16254/Q15329 |
purity: | Affinity chromatography |
Background: |
E2F4 Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-4 binds with high affinity to RBL1 and RBL2. In some instances, can also bind RB protein. Belongs to the E2F/DP family. Component of the DRTF1/E2F transcription factor complex. Binds cooperatively with DP-1 to E2F sites |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 44 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human E2F4 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | E2F transcription factor 4, p107/p130-binding, E2F-4, E2F4, p107/p130-binding protein, Transcription factor E2F4 |
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