| No | Size | Price | Availability | |
| ARP10018-61 | 50ul | 1500.00 | In Stock |  |
| ARP10018-61 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 10018 |
| Isotype: | IgG | Swiss Prot: | O43521 |
| purity: | Affinity chromatography |
| Background: |
| Bim a pro-apoptotic member of the BCL-2 protein family. Interacts with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and act as an apoptotic activator. Its expression can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role in neuronal and lymphocyte apoptosis. Transgenic studies in the mouse suggested that this protein functions as an essential initiator of the apoptosis in thymocyte-negative selection. Eight alternatively spliced transcript variants of this gene have been reported. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 22,25 kDa |
| Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
| Immunogen | A synthetic peptide derived from human BIM |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | B2L11, BAM, bcl-2 interacting mediator of cell death, bcl-2 interacting protein Bim, Bcl-2-like protein 11, bcl-2-related ovarian death agonist, Bcl2-interacting mediator of cell death, Bcl2-L-11, BCL2-like 11 (apoptosis facilitator), BCL2L11, BIM, BIM-a |
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