| No | Size | Price | Availability | |
| ARP7408P-02 | 50ul | 1500.00 | In Stock |  |
| ARP7408P-02 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7408 |
| Isotype: | IgG | Swiss Prot: | P50552 |
| purity: | Affinity purification |
| Background: |
| Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 50 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
|
| Immunogen | A phospho specific peptide corresponding to residues surrounding S239 of human VASP |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | VASP |
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