| No | Size | Price | Availability | |
| ARP1072P-01 | 50ul | 1500.00 | In Stock |  |
| ARP1072P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1072 |
| Isotype: | IgG | Swiss Prot: | P23528 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 19 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:50-1:100
IF 1:100-1:200
|
| Immunogen | A phospho specific peptide corresponding to residues surrounding S3 of human CFL1 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CFL, CFL1, p18, Cofilin 1 |
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