Source: | Rabbit | Gene Id: | 695 |
Isotype: | IgG | Swiss Prot: | Q06187 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IF |
Clonality | Polyclonal Antibody |
Calculated MW | 76 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IF 1:20-1:100
|
Immunogen | A phospho specific peptide corresponding to residues surrounding Y223 of human Btk |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK1 |
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