Phospho-H2AFX-Ser139 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP3014P-01 50ul 1500.00 In Stock
ARP3014P-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 3014
Isotype: IgG Swiss Prot: P16104
purity: Affinity purification
Background:
Histone H2A.X belongs to the histone H2A family, which is synthesized in G1 and S phase. It is involved in nucleosomal organization of chromatin together with other histone proteins, and is specially important for recombination between immunoglobulin switch regions. H2A.X becomes phosphorylated on serine 139 (to form gamma-H2AFX or H2AX139ph) in response to DNA double strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks, which promotes DNA repair and maintains genomic stability.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW 14 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:50-1:200
IF 1:50-1:200
Immunogen A phospho specific peptide corresponding to residues surrounding S139 of human Histone H2Ax
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym H2A.X, H2A/X, H2AX
This product is for research use only, not for diagnostic or therapeutic use!

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