LRP6 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP4040-01 50ul 1500.00 In Stock
ARP4040-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 4040
Isotype: IgG Swiss Prot: O75581
purity: Affinity purification
Background:
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 180 kDa
Recommended Dilutions
WB 1:500-1:1000
IHC 1:10-1:50
Immunogen A synthetic peptide of human LRP6
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym ADCAD2
This product is for research use only, not for diagnostic or therapeutic use!

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