ERBB4 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP2066-11 50ul 1500.00 In Stock
ARP2066-11 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 2066
Isotype: / Swiss Prot: Q15303
purity: Protein G purification
Background:
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Reactivity Human
Tested applications WB IHC ELISA
Clonality Polyclonal Antibody
Calculated MW 180 kDa
Recommended Dilutions
WB 1:100-1:500
IHC 1:50-1:100
Immunogen A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human ERBB4
Storage Store at 4°C. For long term storage store at -20°C in PBS with 0.09% sodium azide. Avoid freeze/thaw cycles.
Synonym HER4, MGC138404
This product is for research use only, not for diagnostic or therapeutic use!

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