| No | Size | Price | Availability | |
| ARP5897-01 | 50ul | 1500.00 | In Stock |  |
| ARP5897-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5897 |
| Isotype: | IgG | Swiss Prot: | P55895 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 59kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
|
| Immunogen | A recombinant protein of human RAG2 |
| Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | RAG-2 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
