UGT1A4 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP54657-01 50ul 1500.00 In Stock
ARP54657-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 54657
Isotype: IgG Swiss Prot: P22310
purity: Affinity purification
Background:
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.
Reactivity Human
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 60kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunogen A recombinant protein of human UGT1A4
Storage Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym UDPGT, UGT1D, UGT-1D, UGT1.4, HUG-BR2, UGT1-04, UDPGT 1-4
This product is for research use only, not for diagnostic or therapeutic use!

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