| No | Size | Price | Availability | |
| ARP1024-11 | 50ul | 1500.00 | In Stock |  |
| ARP1024-11 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1024 |
| Isotype: | IgG | Swiss Prot: | P49336 |
| purity: | Affinity purification |
| Background: |
| The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. |
| Reactivity | Human |
| Tested applications | WB ELISA |
| Clonality | Polyclonal Antibody |
| Calculated MW | 53 kDa |
| Recommended Dilutions |
WB 1:100-1:500
|
| Immunogen | A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human CDK8 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | K35, MGC12607, MGC126075 |
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