PRKAB2 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP5565-01 50ul 1500.00 In Stock
ARP5565-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5565
Isotype: IgG Swiss Prot: O43741
purity: Affinity purification
Background:
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
Reactivity Human, Mouse, Rat
Tested applications WB
Clonality Polyclonal Antibody
Calculated MW 30 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A recombinant protein of human PRKAB2
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym MGC61468
This product is for research use only, not for diagnostic or therapeutic use!

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