GAP43 Rabbit Polyclonal Antibody
No Size Price Availability  
ARP2596-01 50ul 1500.00 In Stock
ARP2596-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 2596
Isotype: IgG Swiss Prot: P17677
purity: Affinity purification
Background:
The neuronal growth-associated protein GAP43 is also known as neuromodulin, B-50, P-57, F1 and pp46. Deficiency of GAP43 in mice results in death early in the postnatal period. GAP43 is one of the main substrates for protein kinase C in the brain. GAP43 is an intracellular growth-associated protein that appears to assist neuronal pathfinding and branching during development and regeneration, and may contribute to presynaptic membrane changes in the adult, leading to the neurotransmitter release, endocytosis and synaptic vesicle recycling, long-term potentiation, spatial memory formation, and learning. The predicated molecular weight of about 25 kDa is much lower than the apparent observed molecular weight of 43 kDa on SDS-PAGE gels, and this occurs because the highly charged nature of GAP43 causes it to bind less than the average amount of SDS per amino acid, and because the protein has an elongated structure.
Reactivity Human, Mouse, Rat
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 25 kDa
Recommended Dilutions
WB 1:500-1:1000
IHC 1:50-1:100
Immunogen A recombinant protein of human GAP43
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym B-50, PP46
This product is for research use only, not for diagnostic or therapeutic use!

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