| No | Size | Price | Availability | |
| ARP8764-01 | 50ul | 1500.00 | In Stock |  |
| ARP8764-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8764 |
| Isotype: | IgG | Swiss Prot: | Q92956 |
| purity: | Affinity purification |
| Background: |
| The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and homeostasis of the immune system. Member 14 of TNFR (TNFRSF14, also named as TR2, ATAR, HVEA, HVEM, LIGHTR) was also identified as a mediator of herpesvirus entry into mammalian cells. The cytoplasmic region of TNFRSF14 bound to several members of the TNFR-associated factor (TRAF) family, namely TRAF1, TRAF2, TRAF3, and TRAF5. Transient transfection into human 293 cells caused marked activation of nuclear factor- B (NF- B), a transcriptional regulator of multiple immunomodulatory and inflammatory genes. |
| Reactivity | Human, |
| Tested applications | WB IHC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 30kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
|
| Immunogen | A recombinant protein of human TNFRSF14 |
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | ATAR, HVEA, HVEM, LIGHTR, TR2 |
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