TAPBP Rabbit Polyclonal Antibody
No Size Price Availability  
ARP6892-01 50ul 1500.00 In Stock
ARP6892-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 6892
Isotype: IgG Swiss Prot: O15533
purity: Affinity purification
Background:
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Reactivity Human, Mouse
Tested applications WB IHC
Clonality Polyclonal Antibody
Calculated MW 47kDa
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunogen A recombinant protein of human TAPBP
Storage Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Synonym TPN, TAPA, TPSN, NGS17
This product is for research use only, not for diagnostic or therapeutic use!

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