
| Source: | Rabbit | Gene Id: | 5434 | 
| Isotype: | IgG | Swiss Prot: | P19388 | 
| purity: | Affinity purification | 
| Background: | 
| This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. | 
| Reactivity | Human, Mouse, Rat | 
| Tested applications | WB IHC | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 24kDa | 
| Recommended Dilutions | 
                                     WB 1:500 - 1:2000 
                                    IHC 1:50 - 1:200 
                                    
                                    
                                    
                                    
                                    
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| Immunogen | A recombinant protein of human POLR2E | 
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | 
| Synonym | RPB5, XAP4, RPABC1, hRPB25, hsRPB5 | 
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