
| Source: | Rabbit | Gene Id: | 5591 | 
| Isotype: | IgG | Swiss Prot: | P78527 | 
| purity: | Affinity purification | 
| Background: | 
| The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku, which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties. | 
| Reactivity | Human, Mouse | 
| Tested applications | WB | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 469 kDa | 
| Recommended Dilutions | 
                                     WB 1:500-1:2000 
                                    
                                    
                                    
                                    
                                    
                                    
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| Immunogen | A synthetic peptide of human PRKDC | 
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350 | 
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