| No | Size | Price | Availability | |
| ARP7048-01 | 50ul | 1500.00 | In Stock |  |
| ARP7048-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 7048 |
| Isotype: | IgG | Swiss Prot: | P37173 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 65 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IF 1:50-1:200
|
| Immunogen | A recombinant protein of human TGFBR2 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII |
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