
| Source: | Rabbit | Gene Id: | 4683 |
| Isotype: | IgG | Swiss Prot: | O60934 |
| purity: | Affinity purification |
| Background: |
| Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
| Reactivity | Human |
| Tested applications | WB IF FC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 62 kDa |
| Recommended Dilutions |
WB 1:500-1:1000
IF 1:20-1:50
FC 1:20-1:50
|
| Immunogen | A synthetic peptide of human NBN |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ATV, NBS, P95, NBS1, AT-V1, AT-V2 |
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