| No | Size | Price | Availability | |
| ARP3726-01 | 50ul | 1500.00 | In Stock |  |
| ARP3726-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3726 |
| Isotype: | IgG | Swiss Prot: | P17275 |
| purity: | Affinity purification |
| Background: |
| JunB is one of the components of the Activator Protein-1 (AP-1) transcription complex that have been implicated in the control ofthe G0/G1 transtion in fibroblasts. AP-1 is a collection of dimers formed by members of the Jun-, Fos-, ATF- and Maf multigene families that bind to specific DNA regulatory elements called AP-1/12-O-tetradecanoylphorbol-13-acetate-responsive elements (TREs) and cAMP-responsive elements (CREs). JunB binds to the DNA sequence 5'-TGA[CG]TCA-3', and involves in the regulation of gene activity following the primary growth factor response. It also acts either as a tumor suppressor or as an oncogene depending on the cell and physiopathological context. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 36 kDa |
| Recommended Dilutions |
WB 1:200-1:2000
IHC 1:50-1:200
IF 1:50-1:100
|
| Immunogen | A recombinant protein of human JUNB |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | AP-1 |
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