Source: | Rabbit | Gene Id: | 7515 |
Isotype: | IgG | Swiss Prot: | P18887 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
Reactivity | Human |
Tested applications | WB IHC IF FC |
Clonality | Polyclonal Antibody |
Calculated MW | 69 kDa |
Recommended Dilutions |
WB 1:500-1:1000
IHC 1:50-1:100
IF 1:20-1:50
FC 1:20-1:50
|
Immunogen | A synthetic peptide of human XRCC1 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | RCC |
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