Source: | Rabbit | Gene Id: | 55272 |
Isotype: | IgG | Swiss Prot: | |
purity: | Purified by Protein A. |
Background: |
Imp3, is a 184 amino acid protein that contains one S4 RNA-binding domain and is the mammalian homolog of the yeast Imp3 protein. Localized to the nucleus, Imp3 exists as a component of a heterotrimeric complex consisting of MPP10, Imp3 and Imp4 and, in this complex, plays a key role in early cleavage events during pre-18S ribosomal processing. The gene encoding Imp3 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human U3 small nucleolar ribonucleoprotein protein IMP3 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | BRMS2, C15orf12, Chromosome 15 open reading frame 12, imp3, IMP3_HUMAN, Mitochondrial ribosomal protein S4, MRPS4, U3 small nucleolar ribonucleoprotein protein imp3, U3 snoRNP protein 3 homolog, U3 snoRNP protein imp3. |
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