Source: | Rabbit | Gene Id: | |
Isotype: | IgG | Swiss Prot: | |
purity: | Purified by Protein A. |
Background: |
Rheumatoid Factor is an antibody that recognizes the Fc portion of immuno-globulin G (IgG). Rheumatoid Factor and IgG form an immune complex that can activate various inflammatory processes in the body. A blood test is clinically used to detect the presence of Rheumatoid Factor, since high levels of Rheumatoid Factor are indicative of rheumatoid arthritis and Sjogren’s syndrome, an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. This factor is also associated with a higher tendency to develop non-joint manifestations of rheumatoid disease, such as rheumatoid nodules and rheumatoid lung disease. |
Reactivity | Human |
Tested applications | IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human Rheumatoid Factor |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | RF, Ig kappa chain V-III region CLL, Rheumatoid factor, KV308_HUMAN. |
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