| No | Size | Price | Availability | |
| YRP09516-01 | 50ul | 1500.00 | In Stock |  |
| YRP09516-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5074 |
| Isotype: | IgG | Swiss Prot: | Q96IZ0 |
| purity: | Purified by Protein A. |
| Background: |
| Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB FC IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
FC 1:20-1:100
|
| Immunogen | KLH conjugated synthetic peptide derived from human PAR4 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | PAR4, Par-4, PRKC apoptosis WT1 regulator protein, Prostate apoptosis response 4 protein, PAWR |
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