Cyclooxygenase 2 Rabbit Polyclonal Antibody
No Size Price Availability  
YRP10416-01 50ul 1500.00 In Stock
YRP10416-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5743
Isotype: IgG Swiss Prot: P35354
purity: Purified by Protein A.
Background:
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Reactivity Human, Mouse, Rat
Tested applications WB IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human Cyclooxygenase 2
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym COX2, COX-2, PHS-2, PGG/HS, PGHS-2, hCox-2, GRIPGHS, Prostaglandin G/H synthase 2, Cyclooxygenase-2, PHS II, Prostaglandin H2 synthase 2, PGH synthase 2, Prostaglandin-endoperoxide synthase 2, PTGS2
This product is for research use only, not for diagnostic or therapeutic use!

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