| No | Size | Price | Availability | |
| YRP09482-01 | 50ul | 1500.00 | In Stock |  |
| YRP09482-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 9659 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.Myomegalin, is a 2,346 amino acid protein that contains one NBPF domain and localizes to the nucleus, cytoplasm, centrosome and Golgi apparatus. Expressed at high levels in fetal and adult heart and at lower levels in brain and placenta, myomegalin is thought to function as an anchoring protein that sequesters members of the cAMP-dependent pathway to the Golgi and to centrosomes, thereby mediating cAMP pathway dynamics. Translocations in the gene that encodes myomegalin are associated with myeloproliferative disorders (MBDs), a group of diseases caused by an overproduction of blood cells. Myomegalin exists as twelve isoforms due to alternative splicing events. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human CMYA2/PDE4DIP |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | Cardiomyopathy associated protein 2, Cardiomyopathy-associated protein 2, CMYA2, MMGL, MYOME_HUMAN, Myomegalin, Pde4dip, Phosphodiesterase 4D interacting protein, Phosphodiesterase 4D-interacting protein. |
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