GPBB Rabbit Polyclonal Antibody
No Size Price Availability  
YRP09458-01 50ul 1500.00 In Stock
YRP09458-01 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 5834
Isotype: IgG Swiss Prot:
purity: Purified by Protein A.
Background:
Glycolysis is an evolutionarily conserved series of ten chemical reactions that utilizes eleven enzymes to concomitantly generate pyruvate and ATP from glucose. fructose kinase-2/fructose 2,6-bisphosphatase (PFK-2) stimulates the synthesis and degradation of fructose 2,6-bisphosphate. Glycogen phosphorylase (also known as GP) is an allosteric enzyme important in carbohydrate metabolism. Its activity is regulated through either noncovalent binding of metabolites or by covalent modification. Glycogen phosphorylase catalyzes the phosphorylation of glycogen to Glc-1-P. There are three genes which encode the brain, liver and muscle forms of glycogen phosphorylase, PYGB, PYGL and PYGM. Because of its fundamental role in the metabolism of glycogen, glycogen phosphorylase has been a target for the design of inhibitory compounds, which could be valuable in the therapeutic treatment of type 2 diabetes mellitus.
Reactivity Human, Mouse, Rat
Tested applications IHC IF
Clonality Polyclonal Antibody
Calculated MW /
Recommended Dilutions
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human GPBB/PYGB
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym Brain glycogen phosphorylase, Glycogen phosphorylase B, Glycogen phosphorylase brain form, Glycogen Phosphorylase Isoenzyme BB, Glycogen phosphorylase, brain form, MGC9213, Phosphorylase glycogen brain, PYGB, PYGB_HUMAN.
This product is for research use only, not for diagnostic or therapeutic use!

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