| No | Size | Price | Availability | |
| YRP09456-01 | 50ul | 1500.00 | In Stock |  |
| YRP09456-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 161882 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human FOG1 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | FOG-1, FOG1_HUMAN, Friend of GATA 1, Friend of GATA protein 1, Friend of GATA1, ZFPM1, Zinc finger protein, Zinc finger protein 89A, Zinc finger protein multitype 1, Zinc finger protein ZFPM1. |
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