| No | Size | Price | Availability | |
| YRP09351-01 | 50ul | 1500.00 | In Stock |  |
| YRP09351-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5706 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| The 26S proteasome is a large complex involved in the intracellular degradation of proteins in eukaryotes. Ubiquitination by E3 ubiquitin ligases targets proteins for degradation by this complex. The 26S proteasome plays an important role in the regulation of many biological processes. It is composed of over 30 different subunits and contains at least two copies of each subunit. Assembly of this large complex is ATP-dependent. Due to its size, it is fairly unstable and often disassociates into subcomplexes (including a 20S core and two 19S regulatory complexes). The 26s proteasome p42A (also known as Rpn7 in yeast and S10 in human) is one of at least nine, non-ATPase lid subunits of the 19S regulatory complex. It is important in the proper assembly and stability of the 26S proteasome. The 19S regulatory complex recognizes ubiquitinated proteins, removes the ubiquitin chains and translocates the proteins to the 20S core for degradation. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human Proteasome 19S 10B |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | 26S protease regulatory subunit 10B, 26S proteasome AAA-ATPase subunit RPT4, Proteasome 26S subunit ATPase 6, Proteasome subunit p42, PRS10, PRS10_HUMAN, PSMC6, SUG2. |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.
