Source: | Rabbit | Gene Id: | 79589 |
Isotype: | IgG | Swiss Prot: | |
purity: | Purified by Protein A. |
Background: |
The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]. |
Reactivity | Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human RNF128 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | E3 ubiquitin protein ligase RNF128, E3 ubiquitin-protein ligase RNF128, FLJ23516, Gene related to anergy in lymphocytes protein, GRAIL, ring finger protein 128, RN128_HUMAN, RNF128. |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.