Source: | Rabbit | Gene Id: | 23295 |
Isotype: | IgG | Swiss Prot: | |
purity: | Purified by Protein A. |
Background: |
E3 ubiquitin-protein ligase. Mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. Plays a role in the regulation of endosome-to-lysosome trafficking. Impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production. Does not inhibit ADRB2-signaling. Does not promote MC1R ubiquitination. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | / |
Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
Immunogen | KLH conjugated synthetic peptide derived from human RNF156 |
Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
Synonym | E3 ubiquitin-protein ligase MGRN1, KIAA0544, Mahogunin ring finger 1, Mahogunin RING finger protein 1, MGRN 1, MGRN1, MGRN1_HUMAN, Probable E3 ubiquitin protein ligase MGRN1, RING finger protein 156, RNF 156. |
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