| No | Size | Price | Availability | |
| YRP09134-01 | 50ul | 1500.00 | In Stock |  |
| YRP09134-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 142689 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B/C complex. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. The largest family of SOCS box-containing proteins is the ankyrin repeat and SOCS box-containing (ASB) protein family. ASB-12 (ankyrin repeat and SOCS box-containing 12) is ag 309 amino acid member of the ASB family that contains one SOCS box domain and five ANK repeats. ASB-12 functions as a substrate-recognition component of an E3 ubiquitin-protein ligase complex and, working in conjunction with other proteins, plays a role in the ubiquitination and subsequent proteasomal degradation of target proteins. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human ASB12 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | ankyrin repeat and SOCS box-containing 12, ankyrin repeat and SOCS box-containing protein 12, ankyrin repeat domain-containing SOCS box protein Asb-12, ASB12, FLJ39577, ASB12_HUMAN. |
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