| No | Size | Price | Availability | |
| YRP09117-01 | 50ul | 1500.00 | In Stock |  |
| YRP09117-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 8623 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| Serotonin, a monoamine neurotransmitter associated with neuronal modulation of emotions, is synthesized by serotonergic neurons of the central nervous system through metabolism of the essential amino acid L-tryptophan. In the pineal gland, serotonin can be transformed into the circadian regulatory hormone melatonin by ASMT (acetylserotonin O-methyltransferase) which catalyzes the final reaction in the synthesis pathway. ASMTL (N-acetylserotonin O-methyltransferase-like protein) is a 621 amino acid protein with a putative catalytic S-adenosyl-L-methionine domain that shares high genetic homology to ASMT. The ASMTL protein is encoded by a gene from the PAR1 region of the X and Y chromosomes, which is considered to be a fusion product of two evolutionarily disparate genes. ASMTL, with potential cytoplasmic localization, is abundant in pancreas, placenta, fibroblast, thymus, prostate, testis, ovary and colon. Low expression levels are found in spleen, small intestine and leukocytes. |
| Reactivity | Human |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human ASMTL |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | Acetylserotonin N methyltransferase like, Acetylserotonin O methyltransferase like, ASMTLX, ASMTLY, ASTML, N acetylserotonin O methyltransferase like protein, ASML_HUMAN. |
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